Hox B4

Case ID:

Detailed Description

Wayne State University researchers are developing a novel therapy which causes hematological leukemia cell lines to undergo apoptosis. While research is in the early stages investigators have shown effectiveness in several cell lines including pre-B acute lymphoblastic leukemia diffuse large cell lymphoma follicular small cleaved cell lymphoma and Waldenstr�m macroglobulinemia. Collectively these cell lines cover almost the entire phenotypic spectrum of B-cell malignancies. While research is in the early stages investigators are excited about this potential new chemotherapeutic treatment. Continuing research will focus on showing the effects of this protein on cancer cells via an intravenous administration route.

File Number: 04-692

Patent Information:
For Information, Contact:
Joan Dunbar
Associate Vice President for Technology Commercialization
Wayne State University
(313) 577-5542
Kamal Mubarak
Ramzi Mohammad
Robert Pauley
Larry Tait