Gene for Chicken Interleukin 15...

Case ID:

Detailed Description

WSU researchers have cloned and patented chicken IL-2 and related avian lymphokines for use as avian vaccine adjuvants. The inventors have shown experimentally that chicken IL-2 can enhance vaccine effectiveness in chickens. Future research to further enable this technology will likely include optimization of delivery methods. IL-2 has a short serum half-life and for maximum efficacy must be attached to or closely associated with the vaccine antigen(s). Various studies have utilized chicken IL-2 fused to antigen expressed by viral vaccine vectors and expressed in DNA vaccines. In general the addition of IL-2 has enhanced both the magnitude and the quality of immune responses. A significant patent portfolio with foreign rights is available.

File Number: 95-344 

Patent Information:
For Information, Contact:
Joan Dunbar
Associate Vice President for Technology Commercialization
Wayne State University
(313) 577-5542
Roy Sundick
Lily Jones
David Smith