Establishment of a Metastatic Prostate Carcinoma Tumor Model in Mice

Case ID:

A Wayne State University researcher has developed new tumorigenic cell lines from the human prostate carcinoma cell line PC-3.  These cell lines, known as PC-3/PI, are highly tumorigenic when implanted in the prostate of nude mice, providing a xenograft tumor model of prostate carcinoma.  In this model, lymph node metastases form from the primary tumor as in human prostate carcinoma. 
Patent Information:
For Information, Contact:
Joan Dunbar
Associate Vice President for Technology Commercialization
Wayne State University
(313) 577-5542
Gilda Hillman
Animal Model
Prostate Cancer
Research Tool