Search Results - epilepsy

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GlyB4 Fusion with Neuregulin Heparin-Targeting Domain to Block Neuregulin Signaling

We have harnessed this natural targeting ability of NRG by fusing the HBD of NRG to soluble HER4. This fusion protein retains high affinity heparin binding to heparin and to cells that express heparan sulfates resulting in a more potent NRG antagonist. In vivo, it is targeted to peripheral nerve segments where it blocks the activity of NRG as a Schwann...

Published: 2/6/2014 | Inventor(s): Jeffrey Loeb, Qunfang Lee

Keywords(s): Anti-cancer, Biotechnology, Cancer risk, Cancer Therapies, Drug Delivery, Drug Target, Epilepsy

Category(s): Life Science, Drug Delivery, Other

Novel Method of Making 3-Dimensional Neural Probes

WSU researchers have developed a unique design for neural probes with both electrical and chemical interfaces, via arrays metal electrodes and micro-channels that can be easily manufactured and folded in 3D arrays. The fabrication process is post-CMOS compatible allowing simple, reliable and cost effective construction of the all the components. Methods...

Published: 2/6/2014 | Inventor(s): Yong Xu, Yuefa Li

Keywords(s): Biotechnology, Drug Delivery, Epilepsy, Microchannels, Neural Probes, Neuroscience

Category(s): Drug Delivery, Life Science, Medical Devices, Other, MEMS, Microfluidics, Physical Sciences, Sensors