Search Results - neuroscience

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Visual Prostheses Based Upon Fiber-Optic Uncaging of Neurotransmitter Substances

Detailed Description A fiber optic cable may also be used to deliver light. The drug delivery system selectively delivers drugs to various types of neurological cells. In operation a solution of photoactivatable neuro-active drug is delivered to a pre-selected area in vivo and photoactivated in the solution at the pre-selected area to stimulate neurological...

Published: 3/31/2014 | Inventor(s): Patrick Mcallister, Raymond Iezzi, Gregory Auner, Gary Abrams

Keywords(s): Drug Delivery, Neurological, Neuroscience

Category(s): Medical, Life Science, Neurological disorders, Therapeutics, Drug Delivery

Novel Dual and Triple Acting CNS Compounds with Potential as Antidepressants, Medications for Attention Deficit Disorders and other Related Neuro-disorders

Wayne State University researchers have identified compounds with a unique molecular template exhibiting reuptake inhibition activity for both at the norepinephrine and serotonin transporters in the CNS. In addition, some of these molecules also exhibit triple reuptake activity for the dopamine, serotonin and norepinephrine transporters. These...

Published: 2/6/2014 | Inventor(s): Aloke Dutta

Keywords(s): Antidepressants, Attention Deficit Disorders, Neuro-disorders, Neuroscience

Category(s): Therapeutics, Diseases, Life Science, Small molecule, Neurological disorders

CNS Compounds Specific for the Monoamine Transporter Systems

The dopamine transporter (DAT) plays an important role in pathophysiological processes in the central nervous system. In cocaine addiction, binding of cocaine to the DAT and consequent blockage of dopamine uptake appears to be related to the reinforcing properties of the drug. Also associated with the transport function is concentration of neurotoxic...

Published: 3/31/2014 | Inventor(s): Aloke Dutta

Keywords(s): Addiction Treatment, Antidepressants, Neuroscience, Parkinson's

Category(s): Therapeutics, Life Science

Novel Method of Making 3-Dimensional Neural Probes

WSU researchers have developed a unique design for neural probes with both electrical and chemical interfaces, via arrays metal electrodes and micro-channels that can be easily manufactured and folded in 3D arrays. The fabrication process is post-CMOS compatible allowing simple, reliable and cost effective construction of the all the components. Methods...

Published: 2/6/2014 | Inventor(s): Yong Xu, Yuefa Li

Keywords(s): Biotechnology, Drug Delivery, Epilepsy, Microchannels, Neural Probes, Neuroscience

Category(s): Drug Delivery, Life Science, Medical Devices, Other, MEMS, Microfluidics, Physical Sciences, Sensors