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Co-polymer Stabilizers for Pressured Metered Dose Inhalers (pMDIs)

A series of novel co polymer surfactants with the general structure LAmEOnLAm were developed along with a Colloidal Probe Microscopy (CPM) method to optimize the surfactant composition using adhesion forces to improve stabilization of drug dispersions. This expands the range of biomolecules and micronized drug particles that can be formulated with pMDIs....

Published: 2/6/2014 | Inventor(s): Sandro Da Rocha, Libo Wu

Keywords(s): Assay, Asthma, Compound, Device, Drug Delivery, Formulation, Instrumentation, Method, Pharmaceuticals, Process, Therapeutics

Category(s): Chemicals, Drug Delivery, Pharmaceuticals, Instrumentation, Materials

Peptide Antimicrobial

In vivo Display Technology for the Isolation of Antimicrobial Peptides Professor Philip R. Cunningham, Ph.D. Department of Biological Sciences @ Wayne State University Interest in peptides as antimicrobial agents has increased dramatically in recent years, driven primarily by the development of new technologies for producing, screening and analyzing...

Published: 2/6/2014 | Inventor(s): Philip Cunningham, Wes Colangelo

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Category(s): Pharmaceuticals, Life Science, Research tools, Assays, Biological materials, Protein/peptides

Peptides Representing Genus-Specific Chlamydial Antigens for Vaccine Peptide Vaccines for Chlamydia to be Delivered Orally or by Other Mucosal Routes

Background Despite increased surveillance and treatment, sexually transmitted disease infections caused by Chlamydia continue to rise. It is estimated that over 20 million new cases of infection occur annually in developed countries, with over 75 million new cases occurring annually in developing countries. Chlamydial genital tract infection is...

Published: 3/31/2014 | Inventor(s): Judith WhittuM-Hudson, Alan Hudson

Keywords(s): Vaccines

Category(s): Pharmaceuticals, Biologicals, Life Science, Therapeutics, Vaccines

Functional Improvements in Fahr Disease

Detailed Description Idiopathic cerebral calcification (a.k.a. Brain Stones) can be associated with a progressive neurological disorder for which there is no known treatment. This invention is a repurposing of an existing FDA approved compound for a new use. It relates to the treatment of Fahr?s Disease by the administration of a class of drugs...

Published: 2/6/2014 | Inventor(s): Jeffrey Loeb

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Category(s): Pharmaceuticals