Search Results - method

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Co-polymer Stabilizers for Pressured Metered Dose Inhalers (pMDIs)

A series of novel co polymer surfactants with the general structure LAmEOnLAm were developed along with a Colloidal Probe Microscopy (CPM) method to optimize the surfactant composition using adhesion forces to improve stabilization of drug dispersions. This expands the range of biomolecules and micronized drug particles that can be formulated with pMDIs....

Published: 2/6/2014 | Inventor(s): Sandro Da Rocha, Libo Wu

Keywords(s): Assay, Asthma, Compound, Device, Drug Delivery, Formulation, Instrumentation, Method, Pharmaceuticals, Process, Therapeutics

Category(s): Chemicals, Drug Delivery, Pharmaceuticals, Instrumentation, Materials

Imaging Tandem Mass Spectrometry: Reduction to Practice

Currently, tandem mass spectrometry is typically performed by selecting a single mass peak in a time of flight or quadrupole mass spectrometer, which is then fragmented through collision, after which the products are mass-selected in a quadrupole or similar secondary mass spectrometer. A Wayne State University researcher has developed an alternative...

Published: 2/6/2014 | Inventor(s): Arthur Suits, Myung Kim, Brian Leskiw

Keywords(s): Diagnostics, Instrumentation, Method

Category(s): Instrumentation, Physical Sciences, Spectroscopy, Imaging, Other

Sub-monolayer detection with surface selective vibrational spectroscopy

This invention describes a new system and method for performing surface-selective spectroscopic detection with high sensitivity and low detection limits particularly in the visible and fingerprint mid-infrared spectral regions. The method offers a substantial improvement, 10-fold or more, over existing techniques. This invention has already been reduced...

Published: 2/6/2014 | Inventor(s): Alexander Benderskii, Igor Stiopkin, Himali Jayathilake

Keywords(s): Device, Instrumentation, Method, Nanotechnology, Optical, Photonic

Category(s): Instrumentation, Spectroscopy, Physical Sciences

A Diagnostic Marker for Matrix Metalloprotease (MMP)-2 and -9 Activity in Cancer Tissue

This invention is a method for the identification of MMP enzyme activity in tissue. MMPs are involved in tumor progression and therefore are targets for anti-cancer drug therapies. However, most drug therapies directed at inhibition of MMPs have failed, in part, because there is no reliable biomarker to determine MMP activity in tissue. This invention...

Published: 3/31/2014 | Inventor(s): Avraham Raz, Rafael Fridman, Pratima NangiA-Maker

Keywords(s): Biomarker, Cancer, Diagnostics, Enzyme, Method

Category(s): Diagnostic, Life Science, Oncology