Search Results - shahriar+mobashery

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Wayne State University researchers have synthesized a series of novel aminoglycoside antibiotics that have shown enhanced antibacterial activity, low susceptibility to existing resistance mechanisms and low toxicity when compared to currently marketed aminoglycosides. Aminoglycoside antibiotics have been used against a wide variety of bacterial...

Published: 2/6/2014 | Inventor(s): Shahriar Mobashery, Lakshmi Kotra, Jalal Haddad

Keywords(s): Antibiotics

Category(s): Therapeutics, Life Science, Small molecule, Diseases, Infectious disease

Inhibitors of Matrix Metalloproteinases

Wayne State University researchers and academic collaborators have prepared the first reported mechanism-based inhibitors for matrix metalloproteinases (MMPs). One of the novel compounds (SB-3CT) shows selectivity for the gelatinases (two members of the MMP family), which have been implicated in various pathological conditions including, but not...

Published: 2/6/2014 | Inventor(s): Shahriar Mobashery, Rafael Fridman

Keywords(s):

Category(s): Therapeutics, Life Science, Small molecule, Diseases