Search Results - infectious+disease

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Loop-Mediated Isothermal Amplification (LAMP) Assay for Meningitis

Summary: A novel LAMP assay has been developed for detection of Neisseria meningitidis (Nm) in patient samples. Six sets of unique primers have been designed which dramatically improve sensitivity of Nm detection and enable discrimination of the six major Nm serogroups (A, B, C, W-135, X, and Y) with limits as low as 1 (one) genomic copy per reaction....

Published: 2/6/2014 | Inventor(s): Mitsuko Seki, Dong Wook Kim, Paul Kilgore

Keywords(s): Diagnostic, Disease, Vaccines

Category(s): Diagnostic, Life Science, Infectious disease, Research tools, Assays

Mannich Bases of Conjugated Styryl Ketones

Detailed Description Human infectious diseases caused by fungi have increased markedly during the past 10 years due mainly to advances in medical care that involve prolonged immune suppression increased use of cytotoxic drugs in cancer chemotherapy and the advent of AIDS. As a result organisms such as Candida albicans have become opportunistic...

Published: 3/31/2014 | Inventor(s): Jonathan Dimmock, Elias Manavathu

Keywords(s): Anti-infective, Therapeutics

Category(s): Therapeutics, Life Science, Infectious disease

Designer Aminoglycosides

Wayne State University researchers have synthesized a series of novel aminoglycoside antibiotics that have shown enhanced antibacterial activity, low susceptibility to existing resistance mechanisms and low toxicity when compared to currently marketed aminoglycosides. Aminoglycoside antibiotics have been used against a wide variety of bacterial...

Published: 2/6/2014 | Inventor(s): Shahriar Mobashery, Lakshmi Kotra, Jalal Haddad

Keywords(s): Antibiotics

Category(s): Therapeutics, Life Science, Small molecule, Diseases, Infectious disease