Search Results - diagnostic

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Loop-Mediated Isothermal Amplification (LAMP) Assay for Meningitis

Summary: A novel LAMP assay has been developed for detection of Neisseria meningitidis (Nm) in patient samples. Six sets of unique primers have been designed which dramatically improve sensitivity of Nm detection and enable discrimination of the six major Nm serogroups (A, B, C, W-135, X, and Y) with limits as low as 1 (one) genomic copy per reaction....

Published: 2/6/2014 | Inventor(s): Mitsuko Seki, Dong Wook Kim, Paul Kilgore

Keywords(s): Diagnostic, Disease, Vaccines

Category(s): Diagnostic, Life Science, Infectious disease, Research tools, Assays

Galectin-3 Single Nucleotide Polymorphism rs4644 Predicts Human Cancer Risk Associated with Racial Disparity

This invention is a new diagnostic tool which allows prediction of cancer risk based on a single nucleotide polymorphism of a gene whose protein is over-expressed in various cancers. The polymorphism results in a single amino acid change. DNA analysis demonstrated that 98% of cancer patients tested had the mutation while normal donors did not....

Published: 3/31/2014 | Inventor(s): Avraham Raz, Pratima NangiA-Maker, Vitaly Balan

Keywords(s): Biotechnology, Cancer, Cancer risk, Diagnostics

Category(s): Diagnostic, Life Science, Oncology

Method For Treating and/or Imaging Breast Cancer Using Radioactive Iodine

This invention involves treating a breast cancer patient by the administration of a radioisotope of iodine in a dosage of between 5 and 50 milliCuries over the course of a day. The therapeutic composition is designed for mammary tissue uptake and includes an inorganic radioactive iodide salt (e.g., alkali metal, alkali earth or transition metal...

Published: 3/31/2014 | Inventor(s): James Rillema

Keywords(s): Anti-cancer, Breast Cancer, Cancer Therapies, Imaging, Therapeutics

Category(s): Therapeutics, Life Science, Oncology, Receptors/targets, Diagnostic, Imaging

SIRT2 Antibody

Detailed Description Studies of yeast have shown that the SIR2 gene family is involved in chromatin structure transcriptional silencing DNA repair and control of cellular life span. Further discussion of this research can be found in Mol Cell Biol. 2003 May 23(9): 3173?3185. File Number: 04-684

Published: 2/6/2014 | Inventor(s): Michael Tainsky, Sylvia Dryden

Keywords(s):

Category(s): Diagnostic

Derivation of Molecular Targets of Cancer and Aging Using Cellular Immortalization-Specific Gene-Expression

Detailed Description WSU faculty developed an approach to identify gene-expression changes in spontaneously immortalized human cell lines as compared to non-immortal cells. This approach led to the identification of molecular targets required for the long lifespan spontaneously acquired by cancer cells. These targets may provide a potential means...

Published: 3/31/2014 | Inventor(s): Sorin Draghici, Olga Studitskaia, Michael Tainsky

Keywords(s): Cancer, Drug Target

Category(s): Diagnostic, Life Science, Oncology

A Diagnostic Marker for Matrix Metalloprotease (MMP)-2 and -9 Activity in Cancer Tissue

This invention is a method for the identification of MMP enzyme activity in tissue. MMPs are involved in tumor progression and therefore are targets for anti-cancer drug therapies. However, most drug therapies directed at inhibition of MMPs have failed, in part, because there is no reliable biomarker to determine MMP activity in tissue. This invention...

Published: 3/31/2014 | Inventor(s): Avraham Raz, Rafael Fridman, Pratima NangiA-Maker

Keywords(s): Biomarker, Cancer, Diagnostics, Enzyme, Method

Category(s): Diagnostic, Life Science, Oncology