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Laser Spray Ionization (LSI) Method for Mass Spectrometry
Imaging
Technology Summary: Laser Spray Ionization (LSI) is a novel inlet ionization method for mass spectrometry invented at WSU which can be used to create predominately multiply charged ions from solid samples at atmospheric pressure. Unlike MALDI ionization methods which are typically limited to producing singly charged species for larger molecules, LSI...
Published: 2/6/2014
|
Inventor(s):
Sarah Trimpin
,
Thushani Nikeshala
,
Ellen Inutan
,
John Maarouf
Keywords(s):
Biotechnology
,
Imaging
Category(s):
Instrumentation
,
Imaging
,
Characterization
,
Other
,
Physical Sciences
,
Spectroscopy
,
Life Science
,
Research tools
Magnetic Resonance Force Microscopy for Molecular
Imaging
Detailed Description Magnetic Resonance Force Microscopy (MRFM) is an emerging technology that combines the strengths of magnetic resonance and force microscopy to achieve high resolution three-dimensional sub-surface
imaging
of a test substance. WSU researchers have adapted and refined MRFM to study biological systems such as isolated cells sub-cellular...
Published: 3/31/2014
|
Inventor(s):
Stanley Fricke
,
Gregory Moore
Keywords(s):
Imaging
Category(s):
Devices
,
Imaging
,
Life Science
,
MRI
Method For Treating and/or
Imaging
Breast Cancer Using Radioactive Iodine
This invention involves treating a breast cancer patient by the administration of a radioisotope of iodine in a dosage of between 5 and 50 milliCuries over the course of a day. The therapeutic composition is designed for mammary tissue uptake and includes an inorganic radioactive iodide salt (e.g., alkali metal, alkali earth or transition metal...
Published: 3/31/2014
|
Inventor(s):
James Rillema
Keywords(s):
Anti-cancer
,
Breast Cancer
,
Cancer Therapies
,
Imaging
,
Therapeutics
Category(s):
Therapeutics
,
Life Science
,
Oncology
,
Receptors/targets
,
Diagnostic
,
Imaging
Imaging
Tandem Mass Spectrometry: Reduction to Practice
Currently, tandem mass spectrometry is typically performed by selecting a single mass peak in a time of flight or quadrupole mass spectrometer, which is then fragmented through collision, after which the products are mass-selected in a quadrupole or similar secondary mass spectrometer. A Wayne State University researcher has developed an alternative...
Published: 2/6/2014
|
Inventor(s):
Arthur Suits
,
Myung Kim
,
Brian Leskiw
Keywords(s):
Diagnostics
,
Instrumentation
,
Method
Category(s):
Instrumentation
,
Physical Sciences
,
Spectroscopy
,
Imaging
,
Other
3D Soundscaping
Researchers at WSU have developed a 3D Soundscaping technology that enables one to take sound measurements to a new level by locating sound sources, visualize their resultant sound pressure fields in 3D space. In traditional sound sensing applications, sound is measured using microphones and sound pressure levels and spectra are measured at survey locations....
Published: 2/6/2014
|
Inventor(s):
Sean Wu
Keywords(s):
Noise
,
Sound
Category(s):
Acoustics
,
Electronics
,
Other
,
Physical Sciences
,
Sensors
,
Software
,
Imaging
Drug-Dendrimer Nanoparticles for Targeted Treatment of Neuroinflammation
Highly effective dendrimer-drug based compositions and methods for treatment have been developed that target neuroinflammation both in the brain and the retina upon intravenous administration. The nanodevices overcome the blood-brain barrier (BBB) and deliver drugs to target cells (activated microglia and astrocytes) producing dramatic therapeutic improvements....
Published: 3/31/2014
|
Inventor(s):
Rangaramanujam Kannan
,
Raymond Iezzi
,
Bharath Rajaguru
,
Sujatha Kannan
Keywords(s):
Alzheimer's Disease
,
Compound
,
Disease
,
Drug Delivery
,
Imaging
,
Nanomaterials
,
Nanotechnology
,
Neural Probes
,
Neuro-disorders
,
Parkinson's
,
Pharmaceuticals
,
Therapeutics
Category(s):
Drug Delivery
,
Therapeutics
,
Diseases
,
Life Science
,
Nano-based
,
Vision
,
Imaging
,
Neurological disorders
,
Dendrimer
Next Generation MRI Contrast
Imaging
Agent
WSU has developed a new class of contrast agents that are effective at ultra-high field strengths (>3 tesla) in magnetic resonance
imaging
(MRI) where current clinical agents severely decline in effectiveness. Our new agents are based on the metal Eu(II) which is novel compared to current agents that are based on Gd(III). The difference between the...
Published: 2/6/2014
|
Inventor(s):
Matthew Allen
,
Nipuni Gamage
,
Yujiang Mei
,
Joel Garcia
,
Jeremiah Moore
Keywords(s):
Compound
,
Diagnostic
,
Imaging
,
MRI
,
Positive
Imaging
Agent
Category(s):
Imaging
,
Chemicals
,
Life Science
,
MRI
,
Physical Sciences
,
Specialty compounds